Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Paclitaxel, Semi-Synthetic
A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.
MilliporeSigma™ Calbiochem™ MMP-2/MMP-9 Inhibitor I
The MMP-2/MMP-9 Inhibitor I, also referenced under CAS 193807-58-8, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Glucagon-Like Peptide 1 Receptor Agonist II
A pyrimidine small molecule that acts as a GLP-1 allosteric agonist that induces cAMP signaling in HEK293 cells expressing the GLP-1 receptor with EC50
MilliporeSigma™ Calbiochem™ HSP90 Inhibitor, CCT018159
The HSP90 Inhibitor, CCT018159, also referenced under CAS 171009-07-7, controls the biological activity of HSP90.
MilliporeSigma™ Calbiochem™ Dipeptidylpeptidase IV Inhibitor I
The Dipeptidylpeptidase IV Inhibitor I controls the biological activity of Dipeptidylpeptidase IV. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ JNK3 Inhibitor XII, SR-3576
The JNK3 Inhibitor XII, SR-3576, also referenced under CAS 1164153-22-3, controls the biological activity of JNK3.
MilliporeSigma™ Calbiochem™ p75NTR Signaling Inhibitor, Cell-permeable, TAT-Pep5
The p75NTR Signaling Inhibitor, Cell-permeable, TAT-Pep5 controls the biological activity of p75NTR. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Pifithrin-μ
Pifithrin-μ, CAS 64984-31-2, is a cell-permeable inhibitor of p53 interaction with Bcl-xL and Bcl-2. Inhibits p53 translocation to mitochondria without affecting the transactivation function of p53.
MilliporeSigma™ Calbiochem™ Jasplakinolide, Jaspis johnstoni
A cell-permeable F-actin probe.
MilliporeSigma™ Calbiochem™ Tau Aggregation Inhibitor, ATPZ, Cpd16
A water soluble (32uM in water) BBB-permeable ATPZ (aminothienopyridazine) tau aggregation inhibitor
MilliporeSigma™ Calbiochem™ TX-1918
A cell-permeable arylidene-cyclopentenedione derived tyrphostin that acts as a potent inhibitor for eEF2-K, while it inhibits other kinases at much higher concentrations.
MilliporeSigma™ Calbiochem™ AG 18
A broad-spectrum protein tyrosine kinase inhibitor.
MilliporeSigma™ Calbiochem™ TRPML Agonist, ML-SA1
The TRPML Agonist, ML-SA1 controls the biological activity of TRPML. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Alendronate, Sodium Salt
An amino-bisphosphonate that acts as a potent inhibitor of bone resorption and cartilage destruction.
MilliporeSigma™ Calbiochem™ Indirubin-3'-monoxime
A potent, reversible, and ATP-compatible inhibitor of GSK-3β (glycogen synthase kinase 3β), Cdk1 (cyclin-dependent kinase1) and Cdk5 (IC50 = 22 nM, 180 nM, and 100 nM, respectively).