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Protease Inhibitors and Phosphatase Inhibitors

Cocktails, tablets, capsules, and individual purified formulations of protease inhibitors and phosphatase inhibitors designed to protect proteins from degradation during cell lysis and extraction.
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136 – 150 of 3,678 results
136

MilliporeSigma™ Calbiochem™ LIM Kinase Inhibitor I, LIMKi 3

The LIM Kinase Inhibitor I, LIMKi 3 controls the biological activity of LIM Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

137

MilliporeSigma™ Calbiochem™ HePTP Inhibitor, ML119

The HePTP Inhibitor, ML119 controls the biological activity of HePTP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

138

MilliporeSigma™ Calbiochem™ Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride

Chemically-modified forskolin with greater stability and water solubility than the parent compound.

Content And Storage Hygroscopic
CAS 115116-37-5
Form Solid
Target Proteins Adenylate cyclase
Solubility MeOH or H2O
Color White
Purity 92% by HPLC
Molecular Formula C29H48N2O7·2HCl
Formula Weight 609.6g/mol
139

MilliporeSigma™ Calbiochem™ β-Glycerophosphate, Disodium Salt, Pentahydrate

A phosphate group donor in matrix mineralization studies that acts as a protein phosphatase inhibitor.

Content And Storage Protect from moisture
CAS 13408-09-8
Form Solid
Target Proteins protein phosphatase
Solubility H2O
Color White
Purity 99% by 31P NMR
Molecular Formula C3H7O6PNa2·5H2O
Formula Weight 306.1g/mol
140

MilliporeSigma™ Calbiochem™ (±)-Ibuprofen

A nonsteroidal anti-inflammatory drug (NSAID) that acts as a reversible and competitive inhibitor of cyclooxygenase 1 (COX-1) (IC50 = 4.85 μM).

141

MilliporeSigma™ Calbiochem™ 1-β-D-Arabinofuranosylcytosine

Anticancer, antiviral agent that is especially effective against leukemias.

142

MilliporeSigma™ Calbiochem™ I-BET

A cell-permeable benzodiazepine compound that binds the tandem bromodomains of BET (bromodomain and extra terminal domain) family members BRD2 (1-473), BRD3 (1-434), and BRD4 (1-477) with high affinity.

143

MilliporeSigma™ Calbiochem™ LY 83583

A cell-permeable, competitive inhibitor of soluble guanylate cyclase (IC50 = 2 μM).

145

MilliporeSigma™ Calbiochem™ γ-Secretase Inhibitor II

The γ-Secretase Inhibitor II controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

146

MilliporeSigma™ Calbiochem™ GSK-3β Inhibitor VIII

The GSK-3β Inhibitor VIII, also referenced under CAS 487021-52-3, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

147

MilliporeSigma™ Calbiochem™ HDAC6 Inhibitor II, BRD9757

A cell-permeable, low molecular weight hydroxamate compound that acts as a potent histone deacetylase class IIb HDAC6-selective inhibitor (IC50 = 30nM), while inhibiting class I HDAC1/2/3/8 only at higher concentrations (IC50

148

MilliporeSigma™ Calbiochem™ LY 294002

LY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC50 = 1.4 μM). Acts on the ATP-binding site.

Content And Storage Protect from light
CAS 154447-36-6
Form Solid
Target Proteins Phosphatidylinositol 3-kinase
Solubility DMSO or EtOH
Color Off-white
Purity 98% by HPLC
Molecular Formula C19H17NO3
Formula Weight 307.4g/mol
149

MilliporeSigma™ Calbiochem™ Sulindac Sulfide

A cell-permeable, active metabolite of Sulindac.

150

MilliporeSigma™ Calbiochem™ Cathepsin B Substrate III, Fluorogenic

Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.